Syphilis under microscope
Syphilis (Treponema pallidum)

Three Ways To Get Tested for Syphilis

Syphilis is normally diagnosed using a urine or a blood sample or by analyzing a specimen (swab) taken from an infected region of the body.

There are three ways to get tested for Syphilis today that don’t require a visit to your doctor or a hospital lab: at-home STD tests, online STD test labs and clinics.

Each type of Syphilis test has its pros and cons.

Reading this on a mobile phone? Take our 60-second quiz to find the right Syphilis test for your needs and budget:

  • mobile-friendly
  • 100% anonymous
  • no strings attached
  • we don’t want your email

NOTE: rotate your phone rotate-phone for best viewing.

Touch an Option to learn more. 

STD Test OptionCostPay w/ Insur.?AccuracyConfi dential?Time (days)Where To BuyDiscounts
Doctor + Lab$200-$500YES99%+NO2-5--
Online Lab $50-$300NO99%+YES0-3STDCheck $10 off
Home Test Kit$25-$200NO< 99%YES0-3MyLabBox Save $10
Free Clinic


The rest of this page explains more about each method.

Good luck!


1. At-Home Syphilis Test Kit

At Home STD Test Syphilis and more

An at-home STD test is an inexpensive way to test for Syphilis. But at-home tests are typically less accurate than a local clinic or an online STD test service.

Also, if you test positive using an at-home test, you may have to purchase a secondary test to confirm the result.

At-home Syphilis tests can be purchased from the following leading retailers:


Learn more about At-Home STD Tests

2. Online STD Test

Want to keep things totally private AND get the most accurate result? 

Then buying an online STD test service is a great choice.

Online Syphilis Tests typically cost between $50 and $250.

STDCheck Test Results
STDCheck Test Results

Where To Buy an Online STD Test

The largest provider of online lab tests in the US is

STDCheck logo 735px

  • With over 4,000 locations, STDCheck is the most popular online STD test provider in the US.
  • Save $10 now
Shop Now & Save $10


Learn more about Online STD Tests

3. Free STD Test Clinic

Free STD Test clinic
Free Test clinics require mandatory counseling

Chances are, there’s a Free STD test clinic near you. Pretty much all of them test for Syphilis. Touch the link below to locate one near you.

CDC Free STD Test Clinic finder

What Is Syphilis?

Syphilis is a relatively rare sexually transmitted infection (STI) caused by the Treponema pallidum bacteria.

Unlike other bacterial STIs like Gonorrhea and Chlamydia, if left untreated Syphilis can cause serious harm to an infected person’s brain, heart and other internal organs. It can also be deadly.

Today, Syphilis is a relatively rare disease in the developed world. According to the CDC, 30,000 to 40,000 cases of syphilis are reported in the United States each year.

How Is Syphillis Transmitted?

Syphillis spreads in the US

Syphilis is transmitted when the infected region touches another person during anal, oral (giving or receiving) and vaginal sex. It cannot be spread through dirty toilets or by casual contact between people. That said,

  • Full sexual penetration is not required to transmit Syphilis.
  • Any contact with infected fluids can transmit the disease.
  • A person infected with Syphilis is considered infectious until the bacteria is thoroughly eliminated.

Since 2000, the number of people contracting syphilis in the U.S. has almost quadrupled, primarily among men who have sex with other men.

Syphillis Risk Factors

People who meet any of the following risk criteria should be regularly tested for Syphilis:

  • have had unprotected sex with a person who may have had syphilis
  • are pregnant
  • are a sex worker
  • are incarcerated
  • are a man who has sex with men

Symptoms of a Syphilis Infection

Often, the first symptom a person infected with Syphilis notices is a chancre – a small, painless sore – on his/her sexual organs, rectum, or inside the mouth. The chancre may go unnoticed for a while.

Syphilis chancre
Syphilis chancre

Syphilis can be difficult to diagnose without an STD test for the following reasons:

  1. An infected person can go years without developing serious and noticeable symptoms. 
  2. If a person develops symptoms, they occur in stages. One stage involves a complete lack of symptoms.

Four Stages of a Syphilis Infection

Syphilis disease progression courtesy WebMedCentral

  1. Primary Syphilis: small and painless chancres develop near the point of contact. These sores are are extremely contagious.  On average, the sore shows up around three weeks after infection, but it can take between 10 and 90 days. The sore remains for anywhere between two and six weeks.
  2. Secondary Syphilis: skin rashes and sore throats are common. The rash is often on the palm and sole of the foot. The rash does not itch. In addition to a rash, people may experience a range of symptoms including headaches, swollen lymph nodes, fever, aching joints and weight loss.
  3. Latent Syphilis: primary and secondary symptoms disappear (for a while).
  4. Tertiary Syphilis: about 30% of people who do not receive treatment will enter this stage. Tertiary syphilis may happen years after initial infection. This is the most serious stage of the disease.

Serious Health Risks Related to Syphilis

The following serious health issues can occur if Syphilis reaches the fourth, tertiary, stage:

  • blindness
  • deafness
  • meningitis
  • heart disease
  • brain infection
  • death
  • mental illness
  • memory loss
  • stroke

Learn More About Syphilis Protection Status